Structural Work

One of the primary functions of the Facility is the 3-dimensional strutcural analysis of new compounds synthesized by researchers. This analysis relies heavily on computational models that describe the data. A few recent examples of structures determined within the facility are presented here.


Siderophores: Important biological agents; highly selective sequestration of iron(III) for uptake by plants.

Potential for chelation therapy in human iron overload diseases.
Challenging to characterize structurally due to flexible nature of compounds.
Compound depicted is the precursor for the iron-free macrolactone.
Org. Lett., 2012, 14(17), 4390.

Mannose Xylose

Organic compounds: natural products, synthetic compounds.
Solid state analysis of compounds; insight from structure led to complementary NMR studies.
Determination of absolute stereochemistry.

Acta Crystallogr. C, 2012, C68, o502.



Solid State NMR